I fly in to SFO a few times a year. I generally don't spend a whole lot of time in the city, but the time I have spent there recently it doesn't strike me as being in any sadder shape than any other major city I have been to recently. Homeless camps seem to be the norm in most big cities. Increased crime, too. SF is a great city. Go. Enjoy.
Disclaimer: I didn't intentionally seek out the worst of it. YMMV
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