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Pill-shooter for the win! Much better than trying to put it in butter; I can dose our cat solo if I wrap her up in a towel (about 80% success first try).
And make sure when you clip nails you are going top-to-bottom. Side to side is very painful for them - I really regret not knowing this for several years w/ our first cat, and things went much better after I wised up.
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