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If you go with a non-runflat the ride will be a lot softer.
My 20" rims wit non-runflat on them (I think 225/35/20 or 225/30/20, not sure but) is a lot softer the my stock 18" rims with runflats (size you mention 225/45/18 ).
And I'm very happy with my Michelin Pilot Super Sports tires (on my summer set). :-)
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