So got a screw in my Alpin PA2 runflat tires after a mere 3k miles - had the tire replaced easily enough, but while at the tire shop (BigO tires) I was stunned by the rep's assertion that on an AWD car, when one tire is replaced you must typically replace ALL tires.
Thankfully, as my car had only ~3300 miles on it, the other tires still had full tread depth, and rep advised I was ok purchasing a single tire. But this was a real shocker/eye-opener for me, having never owned an AWD car before.
Some details re: the issue at...
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http://www.tirerack.com/tires/tirete....jsp?techid=18
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http://askville.amazon.com/replace-t...uestId=2651049